| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Samarth Kulkarni | Chief Executive Officer | 2025-10-17 | 50,895 | $67.91 | $3.46MSell |
| Samarth Kulkarni | Chief Executive Officer | 2025-10-14 | 4,242 | $66.60 | $282.52kSell |
| James R. Kasinger | General Counsel and Secretary | 2025-10-14 | 1,076 | $66.60 | $71.66kSell |
| Samarth Kulkarni | Chief Executive Officer | 2025-08-18 | 13,081 | $58.15 | $760.66kSell |
| Douglas A. Treco | Director | 2025-08-06 | 20,000 | $57.03 | $1.14MBuy |
| Simeon George | Director | 2025-07-16 | 22,319 | $52.03 | $1.16MBuy |
| Simeon George | Director | 2025-07-16 | 960,983 | $52.03 | $50.00MBuy |
| Simeon George | Director | 2025-07-16 | 6,510 | $52.03 | $338.72kBuy |
| Naimish Patel | Chief Medical Officer | 2025-05-29 | 3,932 | $35.94 | $141.32kSell |
| Samarth Kulkarni | Chief Executive Officer | 2025-03-21 | 10,031 | $41.23 | $413.58kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Ark Investment Management LLC | 10.27% | 9,786,973 | $554.73M | Institution |
| Celgene Corp | 8.98% | 8,557,514 | $485.04M | Insider |
| Blackrock Inc | 7.40% | 7,050,145 | $399.60M | Institution |
| Capital International Investors | 5.93% | 5,649,258 | $320.20M | Institution |
| Vertex Pharmaceuticals Europe Ltd | 5.65% | 5,380,940 | $304.99M | Insider |
| Simeon George | 5.52% | 5,259,390 | $298.10M | Insider |
| Bayer Global Investments Bv | 5.36% | 5,105,330 | $289.37M | Insider |
| Orbis Allan Gray Ltd | 5.23% | 4,982,085 | $282.38M | Institution |
| State Street Corp | 4.20% | 4,007,233 | $227.13M | Institution |
| T Rowe Price Investment Management Inc | 3.44% | 3,282,584 | $186.06M | Institution |