| Name | Role | Date | Shares | Price | Value |
|---|---|---|---|---|---|
| Da Silva Jorge Santos | Chief Executive Officer | 2025-12-09 | 70,000 | $14.49 | $1.01MSell |
| Kristian Reich | Chief Scientific Officer | 2025-12-09 | 72,908 | $14.43 | $1.05MSell |
| Kristian Reich | Chief Scientific Officer | 2025-12-08 | 130,000 | $15.08 | $1.96MSell |
| Da Silva Jorge Santos | Chief Executive Officer | 2025-12-08 | 130,000 | $15.08 | $1.96MSell |
| Matthias Bodenstedt | Chief Financial Officer | 2025-10-08 | 10,870 | $9.09 | $98.81kBuy |
| Bihua Chen | Insider | 2025-09-30 | 5,827 | $6.96 | $40.56kSell |
| Bihua Chen | Insider | 2025-09-29 | 2,800,000 | $6.61 | $18.51MSell |
| Bihua Chen | Insider | 2025-09-29 | 3,390,943 | $7.58 | $25.70MSell |
| Bihua Chen | Insider | 2025-09-29 | 232,460 | $8.40 | $1.95MSell |
| Bihua Chen | Insider | 2025-09-29 | 70,748 | $9.38 | $663.62kSell |
| Name | Hold | Shares | Value | Type |
|---|---|---|---|---|
| Bvf Inc | 30.75% | 19,751,284 | $292.12M | Institution |
| Bihua Chen | 7.54% | 4,844,173 | $71.65M | Insider |
| Helix Holdings LLC | 5.01% | 3,215,000 | $47.55M | Insider |
| Kristian Reich | 4.63% | 2,974,551 | $43.99M | Insider |
| Da Silva Jorge Santos | 4.48% | 2,878,577 | $42.57M | Insider |
| Avoro Capital Advisors LLC | 3.11% | 2,000,000 | $29.58M | Institution |
| Cormorant Asset Management LP | 3.10% | 1,994,173 | $29.49M | Institution |
| Balyasny Asset Management LP | 2.65% | 1,699,235 | $25.13M | Institution |
| Adage Capital Partners GP LLC | 2.34% | 1,500,000 | $22.19M | Institution |
| Bvf Partners L P | 2.00% | 1,287,768 | $19.05M | Insider |