NASDAQ: PTGX
Protagonist Therapeutics Inc Stock

$103.88+3.93 (+3.93%)
Updated May 13, 2026
PTGX Price
$103.88
Fair Value Price
-$3.98
Market Cap
$6.68B
52 Week Low
$43.47
52 Week High
$107.84
P/E
-57.39x
P/B
10.19x
P/S
92.63x
PEG
N/A
Dividend Yield
N/A
Revenue
$74.06M
Earnings
-$114.71M
Gross Margin
100%
Operating Margin
-155.78%
Profit Margin
-154.9%
Debt to Equity
0.06
Operating Cash Flow
-$117M
Beta
1.02
Next Earnings
N/A
Ex-Dividend
N/A
Next Dividend
N/A

PTGX Overview

Protagonist Therapeutics, Inc., a biopharmaceutical company, discovers and develops peptide-based therapeutic drugs to address hematology and blood disorders, and inflammatory and immunomodulatory diseases. It is developing rusfertide (PTG-300), an injectable hepcidin mimetic that is in Phase II clinical trials for the treatment of patients with polycythemia vera and hereditary hemochromatosis, as well as for the treatment of other blood disorders; PN-943, an oral, alpha-4-beta-7 integrin- specific antagonist peptide that is in Phase II clinical trials for treating inflammatory bowel disease (IBD); and PN-235, an orally delivered interleukin-23 receptor specific antagonist for the treatment of IBD and non-IBD indications. The company has a license and collaboration agreement with Janssen Biotech, Inc. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.

Zen Rating

Our proven quant model uses 115 proprietary factors, including AI, to determine PTGX's potential to beat the market

AStrong Buy
  • Stocks with a Zen Rating of Strong Buy (A) had an average return of +32.52% per year. Learn More

Zen Rating Component Grades

C
Zen Rating uses advanced AI algorithms that detect subtle patterns in market data; it anticipates future trends that point to superior stock price results.

Industry: Biotech

Industry Rating
F
PTGX
Ranked
#7 of 460

Top Ranked Stocks in Industry

Name / TickerPriceZen Rating
$232.33A
$51.29A
$16.03A
View Top Biotech Stocks

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PTGX News

Overview

Due Diligence Score

Industry Average (25)
You've viewed Due Diligence Score for 10/10 free stocks. Upgrade to Premium to see how PTGX scored across 33 valuation, financial, forecast, performance, and dividend due diligence checks.

Due Diligence Checks

PTGX ($103.88) is overvalued by 2,710.42% relative to our estimate of its Fair Value price of -$3.98 based on Discounted Cash Flow (DCF) modelling
Below Fair Value Valuation
PTGX ($103.88) is not significantly undervalued (2,710.42%) relative to our estimate of its Fair Value price of -$3.98 based on Discounted Cash Flow (DCF) modelling, when including a healthy margin of safety
Significantly Below Fair Value Valuation
PTGX is unprofitable, so we... subscribe to Premium to read more.
Below Benjamin Graham Formula Value Valuation
There are 30 more PTGX due diligence checks available for Premium users.

Valuation

PTGX fair value

Fair Value of PTGX stock based on Discounted Cash Flow (DCF)

Price
$103.88
Fair Value
-$3.98
Undervalued by
2,710.42%
PTGX ($103.88) is overvalued by... subscribe to Premium to read more.
Below Fair Value Valuation
PTGX ($103.88) is not significantly... subscribe to Premium to read more.
Significantly Below Fair Value Valuation
PTGX is unprofitable, so we... subscribe to Premium to read more.
Below Benjamin Graham Formula Value Valuation

PTGX price to earnings (PE)

For valuing profitable companies with steady earnings

Company
-57.39x
Industry
17.32x
Market
22.57x

PTGX price to book (PB)

For valuing companies that are loss-making or have lots of physical asset

Company
10.19x
Industry
5.03x
PTGX is poor value based... subscribe to Premium to read more.
P/B vs Industry Valuation

PTGX's financial health

Profit margin

Revenue
$56.4M
Net Income
$3.8M
Profit Margin
6.7%
PTGX's cash burn is expected... subscribe to Premium to read more.
Interest Coverage Financials
PTGX's profit margin has decreased... subscribe to Premium to read more.
Profit Margin Growth Financials

Assets to liabilities

Assets
$697.5M
Liabilities
$42.0M
Debt to equity
0.06
PTGX's short-term assets ($613.46M) exceed... subscribe to Premium to read more.
Short-term Liabilities Financials
PTGX's short-term assets ($613.46M) exceed... subscribe to Premium to read more.
Long-term Liabilities Financials
PTGX's debt relative to shareholder... subscribe to Premium to read more.
Shrinking Debt Financials
PTGX's debt to equity ratio... subscribe to Premium to read more.
Healthy Debt to Equity Financials

Cash flow

Operating
-$48.9M
Investing
$90.9M
Financing
$23.4M
PTGX's cash and short-term investments... subscribe to Premium to read more.
Debt Coverage Financials

PTGX vs Biotech Stocks

TickerZen RatingMarket Cap1d %P/EP/B
PTGXA$6.68B+3.93%-57.39x10.19x
MIRMD$6.66B+2.13%-8.02x27.45x
SYRED$6.63B+1.69%-36.00x9.88x
TGTXC$6.53B+0.26%13.25x11.20x
CGOND$6.53B+2.68%-31.76x5.98x

Protagonist Therapeutics Stock FAQ

What is Protagonist Therapeutics's quote symbol?

(NASDAQ: PTGX) Protagonist Therapeutics trades on the NASDAQ under the ticker symbol PTGX. Protagonist Therapeutics stock quotes can also be displayed as NASDAQ: PTGX.

If you're new to stock investing, here's how to buy Protagonist Therapeutics stock.

What is the 52 week high and low for Protagonist Therapeutics (NASDAQ: PTGX)?

(NASDAQ: PTGX) Protagonist Therapeutics's 52-week high was $107.84, and its 52-week low was $43.47. It is currently -3.67% from its 52-week high and 139% from its 52-week low.

How much is Protagonist Therapeutics stock worth today?

(NASDAQ: PTGX) Protagonist Therapeutics currently has 64,311,373 outstanding shares. With Protagonist Therapeutics stock trading at $103.88 per share, the total value of Protagonist Therapeutics stock (market capitalization) is $6.68B.

Protagonist Therapeutics stock was originally listed at a price of $11.70 in Aug 11, 2016. If you had invested in Protagonist Therapeutics stock at $11.70, your return over the last 9 years would have been 787.86%, for an annualized return of 27.46% (not including any dividends or dividend reinvestments).

How much is Protagonist Therapeutics's stock price per share?

(NASDAQ: PTGX) Protagonist Therapeutics stock price per share is $103.88 today (as of May 13, 2026).

What is Protagonist Therapeutics's Market Cap?

(NASDAQ: PTGX) Protagonist Therapeutics's market cap is $6.68B, as of May 14, 2026.

Market cap (market capitalization) is the total market value of a publicly traded company's outstanding shares.

Protagonist Therapeutics's market cap is calculated by multiplying PTGX's current stock price of $103.88 by PTGX's total outstanding shares of 64,311,373.
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Information is provided 'as-is' and solely for informational purposes and is not advice. WallStreetZen does not bear any responsibility for any losses or damage that may occur as a result of reliance on this data.